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Specific role of RhoC in tumor invasion and metastasis

Rho GTPases are regulators of many cellular functions and are often dysregulated in cancer. However, the precise role of Rho proteins for tumor development is not well understood. In breast cancer, overexpression of RhoC is linked with poor prognosis. Here, we aim to compare the function of RhoC and...

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Detalles Bibliográficos
Autores principales: Lang, Sarah, Busch, Hauke, Boerries, Melanie, Brummer, Tilman, Timme, Sylvia, Lassmann, Silke, Aktories, Klaus, Schmidt, Gudula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675639/
https://www.ncbi.nlm.nih.gov/pubmed/29152087
http://dx.doi.org/10.18632/oncotarget.20957