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Aspirin exerts high anti-cancer activity in PIK3CA-mutant colon cancer cells

Evidence suggests that nonsteroidal anti-inflammatory drug aspirin (acetylsalicylic acid) may improve patient survival in PIK3CA-mutant colorectal carcinoma, but not in PIK3CA-wild-type carcinoma. However, whether aspirin directly influences the viability of PIK3CA-mutant colon cancer cells is poorl...

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Detalles Bibliográficos
Autores principales:	Gu, Mancang, Nishihara, Reiko, Chen, Yang, Li, Wanwan, Shi, Yan, Masugi, Yohei, Hamada, Tsuyoshi, Kosumi, Keisuke, Liu, Li, da Silva, Annacarolina, Nowak, Jonathan A., Twombly, Tyler, Du, Chunxia, Koh, Hideo, Li, Wenbin, Meyerhardt, Jeffrey A., Wolpin, Brian M., Giannakis, Marios, Aguirre, Andrew J., Bass, Adam J., Drew, David A., Chan, Andrew T., Fuchs, Charles S., Qian, Zhi Rong, Ogino, Shuji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675640/ https://www.ncbi.nlm.nih.gov/pubmed/29152088 http://dx.doi.org/10.18632/oncotarget.20972

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