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High glucose downregulates myocardin expression in rat glomerular mesangial cells via the ERK signaling pathway
Mesangial cells (MCs), which are vascular smooth muscle-derived cells, occupy the central position in the glomerulus. Diabetic nephropathy (DN) is one of the most common diabetes complications and is likely attributed to the loss of MC contractility. Myocardin stimulates downstream vascular smooth m...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675641/ https://www.ncbi.nlm.nih.gov/pubmed/29152089 http://dx.doi.org/10.18632/oncotarget.20498 |