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High glucose downregulates myocardin expression in rat glomerular mesangial cells via the ERK signaling pathway

Mesangial cells (MCs), which are vascular smooth muscle-derived cells, occupy the central position in the glomerulus. Diabetic nephropathy (DN) is one of the most common diabetes complications and is likely attributed to the loss of MC contractility. Myocardin stimulates downstream vascular smooth m...

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Detalles Bibliográficos
Autores principales: Li, Ming, Xu, Lijuan, Feng, Guowei, Zhang, Yan, Wang, Xin, Wang, Yuebing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675641/
https://www.ncbi.nlm.nih.gov/pubmed/29152089
http://dx.doi.org/10.18632/oncotarget.20498