Cargando…
High glucose downregulates myocardin expression in rat glomerular mesangial cells via the ERK signaling pathway
Mesangial cells (MCs), which are vascular smooth muscle-derived cells, occupy the central position in the glomerulus. Diabetic nephropathy (DN) is one of the most common diabetes complications and is likely attributed to the loss of MC contractility. Myocardin stimulates downstream vascular smooth m...
Autores principales: | Li, Ming, Xu, Lijuan, Feng, Guowei, Zhang, Yan, Wang, Xin, Wang, Yuebing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675641/ https://www.ncbi.nlm.nih.gov/pubmed/29152089 http://dx.doi.org/10.18632/oncotarget.20498 |
Ejemplares similares
-
Angiotensin II and the ERK pathway mediate the induction of myocardin by hypoxia in cultured rat neonatal cardiomyocytes
por: Chiu, Chiung-Zuan, et al.
Publicado: (2010) -
Effects of Dangguibuxue decoction on rat glomerular mesangial cells cultured under high glucose conditions
por: Ren, Xiao-Dan, et al.
Publicado: (2017) -
Caveolin-1 is involved in high glucose accelerated human glomerular mesangial cell senescence
por: Feng, Xin, et al.
Publicado: (2017) -
Pathophysiology of mesangial expansion in diabetic nephropathy: mesangial structure, glomerular biomechanics, and biochemical signaling and regulation
por: Thomas, Haryana Y., et al.
Publicado: (2022) -
Effects of bradykinin on proliferation, apoptosis, and cycle of glomerular mesangial cells via the TGF-β1/Smad signaling pathway
por: DONG, Ji, et al.
Publicado: (2021)