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Fibroblast growth factor-2-mediated protection of cardiomyocytes from the toxic effects of doxorubicin requires the mTOR/Nrf-2/HO-1 pathway

BACKGROUND: Cardiotoxic side effects impose limits to the use of anti-tumour chemotherapeutic drugs such as doxorubicin (Dox). There is a need for cardioprotective strategies to prevent the multiple deleterious effects of Dox. Here, we examined the ability of administered fibroblast growth factor-2...

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Detalles Bibliográficos
Autores principales:	Koleini, Navid, Nickel, Barbara E., Wang, Jie, Roveimiab, Zeinab, Fandrich, Robert R., Kirshenbaum, Lorrie A., Cattini, Peter A., Kardami, Elissavet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675643/ https://www.ncbi.nlm.nih.gov/pubmed/29152091 http://dx.doi.org/10.18632/oncotarget.20558

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