The non-canonical ubiquitin activating enzyme UBA6 suppresses epithelial-mesenchymal transition of mammary epithelial cells

Ubiquitination plays critical roles in the regulation of oncoproteins and tumor suppressors during carcinogenesis. The two ubiquitin activating enzymes (E1) in human genome, UBA1 and UBA6, initiate ubiquitination by ATP-dependent activation of ubiquitin. Recent evidence suggests that UBA1 and UBA6 p...

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Detalles Bibliográficos
Autores principales: Liu, Xianpeng, Sun, Limin, Gursel, Demirkan B., Cheng, Chonghui, Huang, Sui, Rademaker, Alfred W., Khan, Seema A., Yin, Jun, Kiyokawa, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675648/
https://www.ncbi.nlm.nih.gov/pubmed/29152096
http://dx.doi.org/10.18632/oncotarget.20900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675648/
https://www.ncbi.nlm.nih.gov/pubmed/29152096
http://dx.doi.org/10.18632/oncotarget.20900

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