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GFAPδ/GFAPα ratio directs astrocytoma gene expression towards a more malignant profile
Astrocytomas are the most common malignant brain tumours and are to date incurable. It is unclear how astrocytomas progress into higher malignant grades. The intermediate filament cytoskeleton is emerging as an important regulator of malignancy in several tumours. The majority of the astrocytomas ex...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675697/ https://www.ncbi.nlm.nih.gov/pubmed/29152145 http://dx.doi.org/10.18632/oncotarget.21540 |