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NADPH oxidase 5 (NOX5)—induced reactive oxygen signaling modulates normoxic HIF‐1α and p27(Kip1) expression in malignant melanoma and other human tumors

NADPH oxidase 5 (NOX5) generated reactive oxygen species (ROS) have been implicated in signaling cascades that regulate cancer cell proliferation. To evaluate and validate NOX5 expression in human tumors, we screened a broad range of tissue microarrays (TMAs), and report substantial overexpression o...

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Detalles Bibliográficos
Autores principales: Antony, Smitha, Jiang, Guojian, Wu, Yongzhong, Meitzler, Jennifer L., Makhlouf, Hala R., Haines, Diana C., Butcher, Donna, Hoon, Dave S., Ji, Jiuping, Zhang, Yiping, Juhasz, Agnes, Lu, Jiamo, Liu, Han, Dahan, Iris, Konate, Mariam, Roy, Krishnendu K., Doroshow, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675809/
https://www.ncbi.nlm.nih.gov/pubmed/28762556
http://dx.doi.org/10.1002/mc.22708