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Chronic NKG2D Engagement In Vivo Differentially Impacts NK Cell Responsiveness by Activating NK Receptors

Immunosuppression is a typical hallmark of cancer and frequently includes perturbations of the NKG2D tumor recognition system as well as impaired signaling by other activating NK cell receptors. Several in vitro studies suggested that sustained engagement of the NKG2D receptor, as it is occurring in...

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Detalles Bibliográficos
Autores principales:	Koch, Christine, Kim, Younghoon, Zöller, Tobias, Born, Christina, Steinle, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675847/ https://www.ncbi.nlm.nih.gov/pubmed/29163533 http://dx.doi.org/10.3389/fimmu.2017.01466

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