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Features of CRISPR-Cas Regulation Key to Highly Efficient and Temporally-Specific crRNA Production
Bacterial immune systems, such as CRISPR-Cas or restriction-modification (R-M) systems, affect bacterial pathogenicity and antibiotic resistance by modulating horizontal gene flow. A model system for CRISPR-Cas regulation, the Type I-E system from Escherichia coli, is silent under standard laborator...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675862/ https://www.ncbi.nlm.nih.gov/pubmed/29163425 http://dx.doi.org/10.3389/fmicb.2017.02139 |