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Central Administration of 5Z-7-Oxozeaenol Protects Experimental Autoimmune Encephalomyelitis Mice by Inhibiting Microglia Activation

Transforming growth factor β-activated kinase 1 (TAK1), a vital upstream integrator of multiple pro-inflammatory signaling pathways, mediates the production of pro-inflammatory cytokines, chemokines, and adhesion molecules. Investigations targeting TAK1 provide new therapeutic options for chronic in...

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Detalles Bibliográficos
Autores principales: Lu, Lingli, Zhang, Xiuping, Tong, Huichun, Zhang, Wenlong, Xu, Pingyi, Qu, Shaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675872/
https://www.ncbi.nlm.nih.gov/pubmed/29163172
http://dx.doi.org/10.3389/fphar.2017.00789