Glutaredoxin-2 controls cardiac mitochondrial dynamics and energetics in mice, and protects against human cardiac pathologies

Glutaredoxin 2 (GRX2), a mitochondrial glutathione-dependent oxidoreductase, is central to glutathione homeostasis and mitochondrial redox, which is crucial in highly metabolic tissues like the heart. Previous research showed that absence of Grx2, leads to impaired mitochondrial complex I function,...

Descripción completa

Detalles Bibliográficos
Autores principales: Kanaan, Georges N., Ichim, Bianca, Gharibeh, Lara, Maharsy, Wael, Patten, David A., Xuan, Jian Ying, Reunov, Arkadiy, Marshall, Philip, Veinot, John, Menzies, Keir, Nemer, Mona, Harper, Mary-Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675898/
https://www.ncbi.nlm.nih.gov/pubmed/29101900
http://dx.doi.org/10.1016/j.redox.2017.10.019

Ejemplares similares

Ejemplares similares