Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) Syndrome with Significant Bilateral Pleural Effusions

We herein report a rare case of a 66-year-old woman who had synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome with marked sternal osteitis and bilateral pleural effusions. SAPHO syndrome was diagnosed based on the characteristic features of a hyperostotic sternum and thoracic spine. T...

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Autores principales: Hasegawa, Shoichi, Yabe, Hiroki, Kaneko, Naoya, Watanabe, Eri, Gono, Takahisa, Terai, Chihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675943/
https://www.ncbi.nlm.nih.gov/pubmed/28924111
http://dx.doi.org/10.2169/internalmedicine.8250-16
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author Hasegawa, Shoichi
Yabe, Hiroki
Kaneko, Naoya
Watanabe, Eri
Gono, Takahisa
Terai, Chihiro
author_facet Hasegawa, Shoichi
Yabe, Hiroki
Kaneko, Naoya
Watanabe, Eri
Gono, Takahisa
Terai, Chihiro
author_sort Hasegawa, Shoichi
collection PubMed
description We herein report a rare case of a 66-year-old woman who had synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome with marked sternal osteitis and bilateral pleural effusions. SAPHO syndrome was diagnosed based on the characteristic features of a hyperostotic sternum and thoracic spine. The inflammatory changes of sternal osteitis and involvement of the adjacent soft tissue were assumed to be the cause of the pleural effusions. The effusions decreased during the natural course of the disease and resolved after methotrexate therapy. The pain dramatically decreased with oral tramadol. Physicians should consider the possibility of SAPHO syndrome in patients with anterior chest pain and pleural effusions.
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spelling pubmed-56759432017-11-13 Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) Syndrome with Significant Bilateral Pleural Effusions Hasegawa, Shoichi Yabe, Hiroki Kaneko, Naoya Watanabe, Eri Gono, Takahisa Terai, Chihiro Intern Med Case Report We herein report a rare case of a 66-year-old woman who had synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome with marked sternal osteitis and bilateral pleural effusions. SAPHO syndrome was diagnosed based on the characteristic features of a hyperostotic sternum and thoracic spine. The inflammatory changes of sternal osteitis and involvement of the adjacent soft tissue were assumed to be the cause of the pleural effusions. The effusions decreased during the natural course of the disease and resolved after methotrexate therapy. The pain dramatically decreased with oral tramadol. Physicians should consider the possibility of SAPHO syndrome in patients with anterior chest pain and pleural effusions. The Japanese Society of Internal Medicine 2017-09-15 2017-10-15 /pmc/articles/PMC5675943/ /pubmed/28924111 http://dx.doi.org/10.2169/internalmedicine.8250-16 Text en Copyright © 2017 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Hasegawa, Shoichi
Yabe, Hiroki
Kaneko, Naoya
Watanabe, Eri
Gono, Takahisa
Terai, Chihiro
Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) Syndrome with Significant Bilateral Pleural Effusions
title Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) Syndrome with Significant Bilateral Pleural Effusions
title_full Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) Syndrome with Significant Bilateral Pleural Effusions
title_fullStr Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) Syndrome with Significant Bilateral Pleural Effusions
title_full_unstemmed Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) Syndrome with Significant Bilateral Pleural Effusions
title_short Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) Syndrome with Significant Bilateral Pleural Effusions
title_sort synovitis-acne-pustulosis-hyperostosis-osteitis (sapho) syndrome with significant bilateral pleural effusions
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675943/
https://www.ncbi.nlm.nih.gov/pubmed/28924111
http://dx.doi.org/10.2169/internalmedicine.8250-16
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