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The envenomation of general physiology throughout the last century
Toxins are the poisonous products of organisms. Toxins serve vital defensive and offensive functions for those that harbor them: stinging scorpions, pesticidal plants, sanguinary snakes, fearless frogs, sliming snails, noxious newts, and smarting spiders. For physiologists, toxins are integral chemi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Rockefeller University Press
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675992/ https://www.ncbi.nlm.nih.gov/pubmed/29021149 http://dx.doi.org/10.1085/jgp.201711856 |
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author | Sack, Jon T. |
author_facet | Sack, Jon T. |
author_sort | Sack, Jon T. |
collection | PubMed |
description | Toxins are the poisonous products of organisms. Toxins serve vital defensive and offensive functions for those that harbor them: stinging scorpions, pesticidal plants, sanguinary snakes, fearless frogs, sliming snails, noxious newts, and smarting spiders. For physiologists, toxins are integral chemical tools that hijack life’s fundamental processes with remarkable molecular specificity. Our understanding of electrophysiological phenomena has been transformed time and time again with the help of some terrifying toxins. For this reason, studies of toxin mechanism are an important and enduring facet of The Journal of General Physiology (JGP). This Milestone in Physiology reflects on toxins studied in JGP over its first 100 years, what they have taught us, and what they have yet to reveal. |
format | Online Article Text |
id | pubmed-5675992 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-56759922018-05-06 The envenomation of general physiology throughout the last century Sack, Jon T. J Gen Physiol Reviews Toxins are the poisonous products of organisms. Toxins serve vital defensive and offensive functions for those that harbor them: stinging scorpions, pesticidal plants, sanguinary snakes, fearless frogs, sliming snails, noxious newts, and smarting spiders. For physiologists, toxins are integral chemical tools that hijack life’s fundamental processes with remarkable molecular specificity. Our understanding of electrophysiological phenomena has been transformed time and time again with the help of some terrifying toxins. For this reason, studies of toxin mechanism are an important and enduring facet of The Journal of General Physiology (JGP). This Milestone in Physiology reflects on toxins studied in JGP over its first 100 years, what they have taught us, and what they have yet to reveal. The Rockefeller University Press 2017-11-06 /pmc/articles/PMC5675992/ /pubmed/29021149 http://dx.doi.org/10.1085/jgp.201711856 Text en © 2017 Sack http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Reviews Sack, Jon T. The envenomation of general physiology throughout the last century |
title | The envenomation of general physiology throughout the last century |
title_full | The envenomation of general physiology throughout the last century |
title_fullStr | The envenomation of general physiology throughout the last century |
title_full_unstemmed | The envenomation of general physiology throughout the last century |
title_short | The envenomation of general physiology throughout the last century |
title_sort | envenomation of general physiology throughout the last century |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675992/ https://www.ncbi.nlm.nih.gov/pubmed/29021149 http://dx.doi.org/10.1085/jgp.201711856 |
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