In vivo properties of the disaggregase function of J‐proteins and Hsc70 in Caenorhabditis elegans stress and aging

Protein aggregation is enhanced upon exposure to various stress conditions and aging, which suggests that the quality control machinery regulating protein homeostasis could exhibit varied capacities in different stages of organismal lifespan. Recently, an efficient metazoan disaggregase activity was...

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Detalles Bibliográficos
Autores principales: Kirstein, Janine, Arnsburg, Kristin, Scior, Annika, Szlachcic, Anna, Guilbride, D. Lys, Morimoto, Richard I., Bukau, Bernd, Nillegoda, Nadinath B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676055/
https://www.ncbi.nlm.nih.gov/pubmed/29024389
http://dx.doi.org/10.1111/acel.12686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676055/
https://www.ncbi.nlm.nih.gov/pubmed/29024389
http://dx.doi.org/10.1111/acel.12686

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