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In vivo properties of the disaggregase function of J‐proteins and Hsc70 in Caenorhabditis elegans stress and aging
Protein aggregation is enhanced upon exposure to various stress conditions and aging, which suggests that the quality control machinery regulating protein homeostasis could exhibit varied capacities in different stages of organismal lifespan. Recently, an efficient metazoan disaggregase activity was...
Autores principales: | Kirstein, Janine, Arnsburg, Kristin, Scior, Annika, Szlachcic, Anna, Guilbride, D. Lys, Morimoto, Richard I., Bukau, Bernd, Nillegoda, Nadinath B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676055/ https://www.ncbi.nlm.nih.gov/pubmed/29024389 http://dx.doi.org/10.1111/acel.12686 |
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