Cargando…

Sexually divergent DNA methylation patterns with hippocampal aging

DNA methylation is a central regulator of genome function, and altered methylation patterns are indicative of biological aging and mortality. Age‐related cellular, biochemical, and molecular changes in the hippocampus lead to cognitive impairments and greater vulnerability to neurodegenerative disea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Masser, Dustin R., Hadad, Niran, Porter, Hunter L., Mangold, Colleen A., Unnikrishnan, Archana, Ford, Matthew M., Giles, Cory B., Georgescu, Constantin, Dozmorov, Mikhail G., Wren, Jonathan D., Richardson, Arlan, Stanford, David R., Freeman, Willard M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676057/ https://www.ncbi.nlm.nih.gov/pubmed/28948711 http://dx.doi.org/10.1111/acel.12681

Ejemplares similares

Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice
por: Hadad, Niran, et al.
Publicado: (2016)

Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging
por: Mangold, Colleen A., et al.
Publicado: (2017)

Role of DNA methylation in the dietary restriction mediated cellular memory
por: Unnikrishnan, Archana, et al.
Publicado: (2017)

Early-life DNA methylation profiles are indicative of age-related transcriptome changes
por: Hadad, Niran, et al.
Publicado: (2019)

The role of DNA methylation in epigenetics of aging
por: Unnikrishnan, Archana, et al.
Publicado: (2018)

Necroptosis increases with age and is reduced by dietary restriction
por: Deepa, Sathyaseelan S., et al.
Publicado: (2018)

Retinal gene expression responses to aging are sexually divergent
por: Du, Mei, et al.
Publicado: (2017)

Many chronological aging clocks can be found throughout the epigenome: Implications for quantifying biological aging
por: Porter, Hunter L., et al.
Publicado: (2021)

Targeting cPLA(2) derived lipid hydroperoxides as a potential intervention for sarcopenia
por: Pharaoh, Gavin, et al.
Publicado: (2020)

Targeted DNA Methylation Analysis by Next-generation Sequencing
por: Masser, Dustin R., et al.
Publicado: (2015)

Use it or lose it: citations predict the continued online availability of published bioinformatics resources
por: Wren, Jonathan D., et al.
Publicado: (2017)

Calorie restriction prevents age-related changes in the intestinal microbiota
por: Kurup, Kavitha, et al.
Publicado: (2021)

Focused, high accuracy 5-methylcytosine quantitation with base resolution by benchtop next-generation sequencing
por: Masser, Dustin R, et al.
Publicado: (2013)

Predicting gene ontology from a global meta-analysis of 1-color microarray experiments
por: Dozmorov, Mikhail G, et al.
Publicado: (2011)

Differential Regulation of Mouse Hippocampal Gene Expression Sex Differences by Chromosomal Content and Gonadal Sex
por: Ocañas, Sarah R., et al.
Publicado: (2022)

Systematic classification of non-coding RNAs by epigenomic similarity
por: Dozmorov, Mikhail G, et al.
Publicado: (2013)

mirCoX: a database of miRNA-mRNA expression correlations derived from RNA-seq meta-analysis
por: Giles, Cory B, et al.
Publicado: (2013)

Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α
por: Mann, Shivani N, et al.
Publicado: (2020)

Effects of transgenic methionine sulfoxide reductase A (MsrA) expression on lifespan and age-dependent changes in metabolic function in mice
por: Salmon, Adam B., et al.
Publicado: (2016)

Litter expansion alters metabolic homeostasis in a sex specific manner
por: Kurup, Kavitha, et al.
Publicado: (2021)

Is Rapamycin a Dietary Restriction Mimetic?
por: Unnikrishnan, Archana, et al.
Publicado: (2020)

Detrimental effects of duplicate reads and low complexity regions on RNA- and ChIP-seq data
por: Dozmorov, Mikhail G, et al.
Publicado: (2015)

Caloric restriction and genomic stability
por: Heydari, Ahmad R., et al.
Publicado: (2007)

MNEMONIC: MetageNomic Experiment Mining to create an OTU Network of Inhabitant Correlations
por: Perz, Aleksandra I., et al.
Publicado: (2019)

The NOTCH3 Downstream Target HEYL Is Required for Efficient Human Airway Basal Cell Differentiation
por: Bodas, Manish, et al.
Publicado: (2021)

ALE: automated label extraction from GEO metadata
por: Giles, Cory B., et al.
Publicado: (2017)

Trends in the production of scientific data analysis resources
por: Hennessey, Jason, et al.
Publicado: (2014)

The Hippocampal Neuroproteome with Aging and Cognitive Decline: Past Progress and Future Directions
por: VanGuilder, Heather D., et al.
Publicado: (2011)

Large-scale directional relationship extraction and resolution
por: Giles, Cory B, et al.
Publicado: (2008)

Divergent Roles of Central Serotonin in Adult Hippocampal Neurogenesis
por: Song, Ning-Ning, et al.
Publicado: (2017)

High-throughput processing and normalization of one-color microarrays for transcriptional meta-analyses
por: Dozmorov, Mikhail G, et al.
Publicado: (2011)

Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia
por: Chucair-Elliott, Ana J., et al.
Publicado: (2020)

Expression profiling of the ubiquitin conjugating enzyme UbcM2 in murine brain reveals modest age-dependent decreases in specific neurons
por: Larabee, Chelsea M., et al.
Publicado: (2015)

A new role for oxidative stress in aging: The accelerated aging phenotype in Sod1(−/)(−) mice is correlated to increased cellular senescence
por: Zhang, Yiqiang, et al.
Publicado: (2016)

Reevaluation of the effect of dietary restriction on different recombinant inbred lines of male and female mice
por: Unnikrishnan, Archana, et al.
Publicado: (2021)

Lifelong reduction in complex IV induces tissue‐specific metabolic effects but does not reduce lifespan or healthspan in mice
por: Deepa, Sathyaseelan S., et al.
Publicado: (2018)

DNA replication timing during development anticipates transcriptional programs and parallels enhancer activation
por: Siefert, Joseph C., et al.
Publicado: (2017)

JNK1 and JNK3: divergent functions in hippocampal metabolic-cognitive function
por: Busquets, Oriol, et al.
Publicado: (2022)

Amygdala activation and GABAergic gene expression in hippocampal sub-regions at the interplay of stress and spatial learning
por: Hadad-Ophir, Osnat, et al.
Publicado: (2014)

Augmenting E Protein Activity Impairs cDC2 Differentiation at the Pre-cDC Stage
por: Bajana, Sandra, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_mucbni9r0f9en924r76h7c1i8q