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In aged primary T cells, mitochondrial stress contributes to telomere attrition measured by a novel imaging flow cytometry assay
The decline of the immune system with age known as immune senescence contributes to inefficient pathogen clearance and is a key risk factor for many aged‐related diseases. However, reversing or halting immune aging requires more knowledge about the cell biology of senescence in immune cells. Telomer...
Autores principales: | Sanderson, Sharon Lesley, Simon, Anna Katharina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676074/ https://www.ncbi.nlm.nih.gov/pubmed/28834142 http://dx.doi.org/10.1111/acel.12640 |
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