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Data on atherosclerosis specific antibody conjugation to nanoemulsions
This article present data related to the publication entitled “Iron oxide core oil-in-water nanoemulsion as tracer for atherosclerosis MPI and MRI imaging” (Prévot et al., 2017) [1]. Herein we describe the engineering in the baculovirus-insect cell system and purification processes of the human scFv...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676083/ https://www.ncbi.nlm.nih.gov/pubmed/29159220 http://dx.doi.org/10.1016/j.dib.2017.10.058 |
| _version_ | 1783277018802028544 |
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| author | Prévot, Geoffrey Duonor-Cérutti, Martine Larivière, Mélusine Laroche-Traineau, Jeanny Jacobin-Valat, Marie Josée Barthélémy, Philippe Clofent-Sanchez, Gisèle Crauste-Manciet, Sylvie |
| author_facet | Prévot, Geoffrey Duonor-Cérutti, Martine Larivière, Mélusine Laroche-Traineau, Jeanny Jacobin-Valat, Marie Josée Barthélémy, Philippe Clofent-Sanchez, Gisèle Crauste-Manciet, Sylvie |
| author_sort | Prévot, Geoffrey |
| collection | PubMed |
| description | This article present data related to the publication entitled “Iron oxide core oil-in-water nanoemulsion as tracer for atherosclerosis MPI and MRI imaging” (Prévot et al., 2017) [1]. Herein we describe the engineering in the baculovirus-insect cell system and purification processes of the human scFv-Fc TEG4-2C antibody, specific of platelets within the atheroma plaque. For molecular targeting purpose, atheroma specific antibody was conjugated to nanoemulsions (NEs) using a heterobifunctional linker (DSPE-PEG-maleimide). Atheroma labelling was assayed by immunochemistry on arterial sections from rabbits. |
| format | Online Article Text |
| id | pubmed-5676083 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-56760832017-11-20 Data on atherosclerosis specific antibody conjugation to nanoemulsions Prévot, Geoffrey Duonor-Cérutti, Martine Larivière, Mélusine Laroche-Traineau, Jeanny Jacobin-Valat, Marie Josée Barthélémy, Philippe Clofent-Sanchez, Gisèle Crauste-Manciet, Sylvie Data Brief Pharmacology, Toxicology and Pharmaceutical Science This article present data related to the publication entitled “Iron oxide core oil-in-water nanoemulsion as tracer for atherosclerosis MPI and MRI imaging” (Prévot et al., 2017) [1]. Herein we describe the engineering in the baculovirus-insect cell system and purification processes of the human scFv-Fc TEG4-2C antibody, specific of platelets within the atheroma plaque. For molecular targeting purpose, atheroma specific antibody was conjugated to nanoemulsions (NEs) using a heterobifunctional linker (DSPE-PEG-maleimide). Atheroma labelling was assayed by immunochemistry on arterial sections from rabbits. Elsevier 2017-10-26 /pmc/articles/PMC5676083/ /pubmed/29159220 http://dx.doi.org/10.1016/j.dib.2017.10.058 Text en © 2017 Published by Elsevier Inc. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Pharmacology, Toxicology and Pharmaceutical Science Prévot, Geoffrey Duonor-Cérutti, Martine Larivière, Mélusine Laroche-Traineau, Jeanny Jacobin-Valat, Marie Josée Barthélémy, Philippe Clofent-Sanchez, Gisèle Crauste-Manciet, Sylvie Data on atherosclerosis specific antibody conjugation to nanoemulsions |
| title | Data on atherosclerosis specific antibody conjugation to nanoemulsions |
| title_full | Data on atherosclerosis specific antibody conjugation to nanoemulsions |
| title_fullStr | Data on atherosclerosis specific antibody conjugation to nanoemulsions |
| title_full_unstemmed | Data on atherosclerosis specific antibody conjugation to nanoemulsions |
| title_short | Data on atherosclerosis specific antibody conjugation to nanoemulsions |
| title_sort | data on atherosclerosis specific antibody conjugation to nanoemulsions |
| topic | Pharmacology, Toxicology and Pharmaceutical Science |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676083/ https://www.ncbi.nlm.nih.gov/pubmed/29159220 http://dx.doi.org/10.1016/j.dib.2017.10.058 |
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