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Tertiary amine synthesis via reductive coupling of amides with Grignard reagents

A new iridium catalyzed reductive coupling reaction of Grignard reagents and tertiary amides affording functionalised tertiary amine products via an efficient and technically-simple one-pot, two-stage experimental protocol, is reported. The reaction – which can be carried out on gram-scale using as...

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Detalles Bibliográficos
Autores principales:	Xie, Lan-Gui, Dixon, Darren J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676097/ https://www.ncbi.nlm.nih.gov/pubmed/29163902 http://dx.doi.org/10.1039/c7sc03613b

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