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Inference of Distribution of Fitness Effects and Proportion of Adaptive Substitutions from Polymorphism Data

The distribution of fitness effects (DFE) encompasses the fraction of deleterious, neutral, and beneficial mutations. It conditions the evolutionary trajectory of populations, as well as the rate of adaptive molecular evolution (α). Inferring DFE and α from patterns of polymorphism, as given through...

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Detalles Bibliográficos
Autores principales:	Tataru, Paula, Mollion, Maéva, Glémin, Sylvain, Bataillon, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2017
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676230/ https://www.ncbi.nlm.nih.gov/pubmed/28951530 http://dx.doi.org/10.1534/genetics.117.300323

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