Cargando…

Inference of Distribution of Fitness Effects and Proportion of Adaptive Substitutions from Polymorphism Data

The distribution of fitness effects (DFE) encompasses the fraction of deleterious, neutral, and beneficial mutations. It conditions the evolutionary trajectory of populations, as well as the rate of adaptive molecular evolution (α). Inferring DFE and α from patterns of polymorphism, as given through...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tataru, Paula, Mollion, Maéva, Glémin, Sylvain, Bataillon, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2017
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676230/ https://www.ncbi.nlm.nih.gov/pubmed/28951530 http://dx.doi.org/10.1534/genetics.117.300323

Ejemplares similares

Inferring the distributions of fitness effects and proportions of strongly deleterious mutations
por: Charmouh, Anders P, et al.
Publicado: (2023)

Hunting for Beneficial Mutations: Conditioning on SIFT Scores When Estimating the Distribution of Fitness Effect of New Mutations
por: Chen, Jun, et al.
Publicado: (2021)

Dioecy Is Associated with High Genetic Diversity and Adaptation Rates in the Plant Genus Silene
por: Muyle, Aline, et al.
Publicado: (2020)

Statistical Inference in the Wright–Fisher Model Using Allele Frequency Data
por: Tataru, Paula, et al.
Publicado: (2017)

The Evolutionary Interplay between Adaptation and Self-Fertilization
por: Hartfield, Matthew, et al.
Publicado: (2017)

Haplotype-based inference of the distribution of fitness effects
por: Ortega-Del Vecchyo, Diego, et al.
Publicado: (2022)

Epistasis and the Structure of Fitness Landscapes: Are Experimental Fitness Landscapes Compatible with Fisher’s Geometric Model?
por: Blanquart, François, et al.
Publicado: (2016)

Patterns of Genome-Wide Nucleotide Diversity in the Gynodioecious Plant Thymus vulgaris Are Compatible with Recent Sweeps of Cytoplasmic Genes
por: Mollion, Maeva, et al.
Publicado: (2017)

Exact Inference for Hardy-Weinberg Proportions with Missing Genotypes: Single and Multiple Imputation
por: Graffelman, Jan, et al.
Publicado: (2015)

Inferring Parameters of the Distribution of Fitness Effects of New Mutations When Beneficial Mutations Are Strongly Advantageous and Rare
por: Booker, Tom R.
Publicado: (2020)

From Drift to Draft: How Much Do Beneficial Mutations Actually Contribute to Predictions of Ohta’s Slightly Deleterious Model of Molecular Evolution?
por: Chen, Jun, et al.
Publicado: (2020)

Inferring Fitness Effects from Time-Resolved Sequence Data with a Delay-Deterministic Model
por: Nené, Nuno R., et al.
Publicado: (2018)

A Framework for Inferring Fitness Landscapes of Patient-Derived Viruses Using Quasispecies Theory
por: Seifert, David, et al.
Publicado: (2015)

Effects of single nucleotide polymorphism ascertainment on population structure inferences
por: Dokan, Kotaro, et al.
Publicado: (2021)

Fluctuations of Fitness Distributions and the Rate of Muller’s Ratchet
por: Neher, Richard A., et al.
Publicado: (2012)

Mutation Rate Inferred From Synonymous Substitutions in a Long-Term Evolution Experiment With Escherichia coli
por: Wielgoss, Sébastien, et al.
Publicado: (2011)

Selective Sweeps Under Dominance and Inbreeding
por: Hartfield, Matthew, et al.
Publicado: (2020)

A Bayesian MCMC Approach to Assess the Complete Distribution of Fitness Effects of New Mutations: Uncovering the Potential for Adaptive Walks in Challenging Environments
por: Bank, Claudia, et al.
Publicado: (2014)

Conflation of Short Identity-by-Descent Segments Bias Their Inferred Length Distribution
por: Chiang, Charleston W. K., et al.
Publicado: (2016)

Bayesian Inference of the Evolution of a Phenotype Distribution on a Phylogenetic Tree
por: Ansari, M. Azim, et al.
Publicado: (2016)

Inferring Past Effective Population Size from Distributions of Coalescent Times
por: Gattepaille, Lucie, et al.
Publicado: (2016)

Inferring the Probability of the Derived vs. the Ancestral Allelic State at a Polymorphic Site
por: Keightley, Peter D., et al.
Publicado: (2018)

Inference of the Distribution of Selection Coefficients for New Nonsynonymous Mutations Using Large Samples
por: Kim, Bernard Y., et al.
Publicado: (2017)

Inference of Purifying and Positive Selection in Three Subspecies of Chimpanzees (Pan troglodytes) from Exome Sequencing
por: Bataillon, Thomas, et al.
Publicado: (2015)

Genetics of adaptation and fitness landscapes: From toy models to testable quantitative predictions
por: Bataillon, Thomas, et al.
Publicado: (2022)

Benchmarking Relatedness Inference Methods with Genome-Wide Data from Thousands of Relatives
por: Ramstetter, Monica D., et al.
Publicado: (2017)

Inferring Ancestral Recombination Graphs from Bacterial Genomic Data
por: Vaughan, Timothy G., et al.
Publicado: (2017)

Inference of Historical Population-Size Changes with Allele-Frequency Data
por: Lynch, Michael, et al.
Publicado: (2019)

Bayesian Inference on Proportional Elections
por: Brunello, Gabriel Hideki Vatanabe, et al.
Publicado: (2015)

From genotype to phenotype: Genetic redundancy and the maintenance of an adaptive polymorphism in the context of high gene flow
por: Bataillon, Thomas, et al.
Publicado: (2022)

On the Distribution of Tract Lengths During Adaptive Introgression
por: Shchur, Vladimir, et al.
Publicado: (2020)

Powerful Inference with the D-Statistic on Low-Coverage Whole-Genome Data
por: Soraggi, Samuele, et al.
Publicado: (2017)

Inferring the Demographic History and Rate of Adaptive Substitution in Drosophila
por: Li, Haipeng, et al.
Publicado: (2006)

Inferring Haplotypes of Copy Number Variations From High-Throughput Data With Uncertainty
por: Kato, Mamoru, et al.
Publicado: (2011)

fastSTRUCTURE: Variational Inference of Population Structure in Large SNP Data Sets
por: Raj, Anil, et al.
Publicado: (2014)

A Bayesian Approach to Inferring the Phylogenetic Structure of Communities from Metagenomic Data
por: O’Brien, John D., et al.
Publicado: (2014)

The Recombination Landscape in Wild House Mice Inferred Using Population Genomic Data
por: Booker, Tom R., et al.
Publicado: (2017)

Joint inference of evolutionary transitions to self-fertilization and demographic history using whole-genome sequences
por: Strütt, Stefan, et al.
Publicado: (2023)

Identification of Polymorphisms Associated with Drought Adaptation QTL in Brassica napus by Resequencing
por: Fletcher, Richard S., et al.
Publicado: (2016)

Inferring Epidemiological Dynamics with Bayesian Coalescent Inference: The Merits of Deterministic and Stochastic Models
por: Popinga, Alex, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ubsqtukjnv8f72ip0q87n44gq5