Allogeneic hematopoietic cell transplantation in an adult patient with Glanzmann thrombasthenia

Glanzmann thrombasthenia is a rare bleeding disorder that can present life‐threatening bleeding. Our patients develop antiplatelet antibodies that become refractory to any pharmacological treatment. Allogeneic hematopoietic stem‐cell transplantation is the only currently curative procedure, but has...

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Detalles Bibliográficos
Autores principales: Cid, Ana R., Montesinos, Pau, Sánchez‐Guiu, Isabel, Haya, Saturnino, Lorenzo, Jose I., Sanz, Jaime, Moscardo, Federico, Puig, Nieves, Planelles, Dolores, Bonanad, Santiago, Sanz, Guillermo F., Vicente, Vicente, González‐Manchón, Consuelo, Lozano, María L., Rivera, José, Sanz, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676254/
https://www.ncbi.nlm.nih.gov/pubmed/29152293
http://dx.doi.org/10.1002/ccr3.1206
Descripción
Sumario:Glanzmann thrombasthenia is a rare bleeding disorder that can present life‐threatening bleeding. Our patients develop antiplatelet antibodies that become refractory to any pharmacological treatment. Allogeneic hematopoietic stem‐cell transplantation is the only currently curative procedure, but has major risks mainly in adult; indeed, our patient died.

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