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Inhibitors of Histone Deacetylases Are Weak Activators of the FMR1 Gene in Fragile X Syndrome Cell Lines

Fragile X syndrome is the most common cause of inherited intellectual disability in humans. It is a result of CGG repeat expansion in the 5′ untranslated region (5′ UTR) of the FMR1 gene. This gene encodes the FMRP protein that is involved in neuronal development. Repeat expansion leads to heterochr...

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Detalles Bibliográficos
Autores principales:	Dolskiy, Alexander A., Pustylnyak, Vladimir O., Yarushkin, Andrey A., Lemskaya, Natalya A., Yudkin, Dmitry V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676349/ https://www.ncbi.nlm.nih.gov/pubmed/29209628 http://dx.doi.org/10.1155/2017/3582601

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