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Study of Carotid Intimal Medial Thickness in Essential Hypertension With or Without Left Ventricular Hypertrophy
INTRODUCTION: Hypertension and atherosclerosis though separate entities, are interrelated as hypertension plays an important role in the pathogenesis of atherosclerosis. This study was undertaken to study the association of carotid intimal medial thickness with left ventricular hypertrophy (LVH) in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676410/ https://www.ncbi.nlm.nih.gov/pubmed/29063904 http://dx.doi.org/10.4103/aam.aam_9_17 |
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author | Khutan, Himanshu Aggarwal, Simmi Kajal, K. S. Garg, Ravinder Kaur, Rupinderjeet Kaur, Amanpreet |
author_facet | Khutan, Himanshu Aggarwal, Simmi Kajal, K. S. Garg, Ravinder Kaur, Rupinderjeet Kaur, Amanpreet |
author_sort | Khutan, Himanshu |
collection | PubMed |
description | INTRODUCTION: Hypertension and atherosclerosis though separate entities, are interrelated as hypertension plays an important role in the pathogenesis of atherosclerosis. This study was undertaken to study the association of carotid intimal medial thickness with left ventricular hypertrophy (LVH) in hypertensive patients. MATERIALS AND METHODS: Hundred hypertensives (JNC-7, Stage 1 and 2) between 30 and 55 years were enrolled in this prospective observational study conducted at a tertiary care teaching institute of Punjab, India. Electrocardiogram, Carotid Doppler, and Echocardiography were carried out in addition to routine biochemical investigations. RESULTS: Increased carotid intimal medial thickness (CIMT) had statistically significant association with age, duration of hypertension, high systolic and diastolic blood pressure (BP), left ventricular hypertrophy and left ventricular mass index but was not associated with body mass index, low-density lipoproteins, and total cholesterol. CONCLUSIONS: LVH and arterial wall changes occur concurrently, and therefore, management of hypertension should not be limited just to control of BP but should also include therapy for carotid plaques and increased CIMT. |
format | Online Article Text |
id | pubmed-5676410 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-56764102017-11-17 Study of Carotid Intimal Medial Thickness in Essential Hypertension With or Without Left Ventricular Hypertrophy Khutan, Himanshu Aggarwal, Simmi Kajal, K. S. Garg, Ravinder Kaur, Rupinderjeet Kaur, Amanpreet Ann Afr Med Original Article INTRODUCTION: Hypertension and atherosclerosis though separate entities, are interrelated as hypertension plays an important role in the pathogenesis of atherosclerosis. This study was undertaken to study the association of carotid intimal medial thickness with left ventricular hypertrophy (LVH) in hypertensive patients. MATERIALS AND METHODS: Hundred hypertensives (JNC-7, Stage 1 and 2) between 30 and 55 years were enrolled in this prospective observational study conducted at a tertiary care teaching institute of Punjab, India. Electrocardiogram, Carotid Doppler, and Echocardiography were carried out in addition to routine biochemical investigations. RESULTS: Increased carotid intimal medial thickness (CIMT) had statistically significant association with age, duration of hypertension, high systolic and diastolic blood pressure (BP), left ventricular hypertrophy and left ventricular mass index but was not associated with body mass index, low-density lipoproteins, and total cholesterol. CONCLUSIONS: LVH and arterial wall changes occur concurrently, and therefore, management of hypertension should not be limited just to control of BP but should also include therapy for carotid plaques and increased CIMT. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5676410/ /pubmed/29063904 http://dx.doi.org/10.4103/aam.aam_9_17 Text en Copyright: © 2017 Annals of African Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Khutan, Himanshu Aggarwal, Simmi Kajal, K. S. Garg, Ravinder Kaur, Rupinderjeet Kaur, Amanpreet Study of Carotid Intimal Medial Thickness in Essential Hypertension With or Without Left Ventricular Hypertrophy |
title | Study of Carotid Intimal Medial Thickness in Essential Hypertension With or Without Left Ventricular Hypertrophy |
title_full | Study of Carotid Intimal Medial Thickness in Essential Hypertension With or Without Left Ventricular Hypertrophy |
title_fullStr | Study of Carotid Intimal Medial Thickness in Essential Hypertension With or Without Left Ventricular Hypertrophy |
title_full_unstemmed | Study of Carotid Intimal Medial Thickness in Essential Hypertension With or Without Left Ventricular Hypertrophy |
title_short | Study of Carotid Intimal Medial Thickness in Essential Hypertension With or Without Left Ventricular Hypertrophy |
title_sort | study of carotid intimal medial thickness in essential hypertension with or without left ventricular hypertrophy |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676410/ https://www.ncbi.nlm.nih.gov/pubmed/29063904 http://dx.doi.org/10.4103/aam.aam_9_17 |
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