Cargando…
Genetic Analysis of LRRK2 R1628P in Parkinson's Disease in Asian Populations
Although the etiology of Parkinson's disease (PD) remains unclear, there is increasing evidence of genetic factors contributing to the onset of PD. Various mutations and risk variants of the gene LRRK2 have been reported, but the association between LRRK2 R1628P and PD is still inconsistent. Th...
Autores principales: | Zhang, Yuan, Sun, Qiying, Yi, Minhan, Zhou, Xun, Guo, Jifeng, Xu, Qian, Tang, Beisha, Yan, Xinxiang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676475/ https://www.ncbi.nlm.nih.gov/pubmed/29209554 http://dx.doi.org/10.1155/2017/8093124 |
Ejemplares similares
-
Relationship between LRRK2 R1628P polymorphism and Parkinson's disease in Asian populations
por: Zhao, Hui, et al.
Publicado: (2016) -
Association of LRRK2 R1628P variant with Parkinson’s disease in Ethnic Han-Chinese and subgroup population
por: Zhang, Pei, et al.
Publicado: (2016) -
LRRK2 G2385R and R1628P Mutations Are Associated with an Increased Risk of Parkinson's Disease in the Malaysian Population
por: Gopalai, Aroma Agape, et al.
Publicado: (2014) -
Parkinson-Related LRRK2 Mutation R1628P Enables Cdk5 Phosphorylation of LRRK2 and Upregulates Its Kinase Activity
por: Shu, Yang, et al.
Publicado: (2016) -
Clinical Heterogeneity Among LRRK2 Variants in Parkinson's Disease: A Meta-Analysis
por: Shu, Li, et al.
Publicado: (2018)