Combinations of QTc-prolonging drugs: towards disentangling pharmacokinetic and pharmacodynamic effects in their potentially additive nature

BACKGROUND: Whether arrhythmia risks will increase if drugs with electrocardiographic (ECG) QT-prolonging properties are combined is generally supposed but not well studied. Based on available evidence, the Arizona Center for Education and Research on Therapeutics (AZCERT) classification defines the...

Descripción completa

Detalles Bibliográficos
Autores principales: Meid, Andreas D., Bighelli, Irene, Mächler, Sarah, Mikus, Gerd, Carrà, Giuseppe, Castellazzi, Mariasole, Lucii, Claudio, Martinotti, Giovanni, Nosè, Michela, Ostuzzi, Giovanni, Barbui, Corrado, Haefeli, Walter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676495/
https://www.ncbi.nlm.nih.gov/pubmed/29201344
http://dx.doi.org/10.1177/2045125317721662

Ejemplares similares

Ejemplares similares