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DNMT3a contributes to the development and maintenance of bone cancer pain by silencing Kv1.2 expression in spinal cord dorsal horn

Metastatic bone tumor-induced changes in gene transcription and translation in pain-related regions of the nervous system may participate in the development and maintenance of bone cancer pain. Epigenetic modifications including DNA methylation regulate gene transcription. Here, we report that intra...

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Detalles Bibliográficos
Autores principales:	Miao, Xue-Rong, Fan, Long-Chang, Wu, Shaogen, Mao, Qing-Xiang, Li, Zhen, Lutz, Brianna M, Xu, Jitian, Lu, Zhi-Jie, Tao, Yuan-Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676500/ https://www.ncbi.nlm.nih.gov/pubmed/29056068 http://dx.doi.org/10.1177/1744806917740681

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