Cargando…
Biosensing Using Magnetic Particle Detection Techniques
Magnetic particles are widely used as signal labels in a variety of biological sensing applications, such as molecular detection and related strategies that rely on ligand-receptor binding. In this review, we explore the fundamental concepts involved in designing magnetic particles for biosensing ap...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676660/ https://www.ncbi.nlm.nih.gov/pubmed/28994727 http://dx.doi.org/10.3390/s17102300 |
_version_ | 1783277096682913792 |
---|---|
author | Chen, Yi-Ting Kolhatkar, Arati G. Zenasni, Oussama Xu, Shoujun Lee, T. Randall |
author_facet | Chen, Yi-Ting Kolhatkar, Arati G. Zenasni, Oussama Xu, Shoujun Lee, T. Randall |
author_sort | Chen, Yi-Ting |
collection | PubMed |
description | Magnetic particles are widely used as signal labels in a variety of biological sensing applications, such as molecular detection and related strategies that rely on ligand-receptor binding. In this review, we explore the fundamental concepts involved in designing magnetic particles for biosensing applications and the techniques used to detect them. First, we briefly describe the magnetic properties that are important for bio-sensing applications and highlight the associated key parameters (such as the starting materials, size, functionalization methods, and bio-conjugation strategies). Subsequently, we focus on magnetic sensing applications that utilize several types of magnetic detection techniques: spintronic sensors, nuclear magnetic resonance (NMR) sensors, superconducting quantum interference devices (SQUIDs), sensors based on the atomic magnetometer (AM), and others. From the studies reported, we note that the size of the MPs is one of the most important factors in choosing a sensing technique. |
format | Online Article Text |
id | pubmed-5676660 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-56766602017-11-17 Biosensing Using Magnetic Particle Detection Techniques Chen, Yi-Ting Kolhatkar, Arati G. Zenasni, Oussama Xu, Shoujun Lee, T. Randall Sensors (Basel) Review Magnetic particles are widely used as signal labels in a variety of biological sensing applications, such as molecular detection and related strategies that rely on ligand-receptor binding. In this review, we explore the fundamental concepts involved in designing magnetic particles for biosensing applications and the techniques used to detect them. First, we briefly describe the magnetic properties that are important for bio-sensing applications and highlight the associated key parameters (such as the starting materials, size, functionalization methods, and bio-conjugation strategies). Subsequently, we focus on magnetic sensing applications that utilize several types of magnetic detection techniques: spintronic sensors, nuclear magnetic resonance (NMR) sensors, superconducting quantum interference devices (SQUIDs), sensors based on the atomic magnetometer (AM), and others. From the studies reported, we note that the size of the MPs is one of the most important factors in choosing a sensing technique. MDPI 2017-10-10 /pmc/articles/PMC5676660/ /pubmed/28994727 http://dx.doi.org/10.3390/s17102300 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Chen, Yi-Ting Kolhatkar, Arati G. Zenasni, Oussama Xu, Shoujun Lee, T. Randall Biosensing Using Magnetic Particle Detection Techniques |
title | Biosensing Using Magnetic Particle Detection Techniques |
title_full | Biosensing Using Magnetic Particle Detection Techniques |
title_fullStr | Biosensing Using Magnetic Particle Detection Techniques |
title_full_unstemmed | Biosensing Using Magnetic Particle Detection Techniques |
title_short | Biosensing Using Magnetic Particle Detection Techniques |
title_sort | biosensing using magnetic particle detection techniques |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676660/ https://www.ncbi.nlm.nih.gov/pubmed/28994727 http://dx.doi.org/10.3390/s17102300 |
work_keys_str_mv | AT chenyiting biosensingusingmagneticparticledetectiontechniques AT kolhatkararatig biosensingusingmagneticparticledetectiontechniques AT zenasnioussama biosensingusingmagneticparticledetectiontechniques AT xushoujun biosensingusingmagneticparticledetectiontechniques AT leetrandall biosensingusingmagneticparticledetectiontechniques |