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Climatic variability and morbidity and mortality associated with particulate matter

OBJECTIVE: The objective of this study has been to analyze whether fine particulate matter (PM(2.5)), as well as its synergistic effect with maximum temperature, humidity, and seasons, is associated with morbidity and mortality from cardiovascular diseases. METHODS: This is an ecological study of ti...

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Autores principales: Rodrigues, Poliany Cristiny de Oliveira, Pinheiro, Samya de Lara, Junger, Washington, Ignotti, Eliane, Hacon, Sandra de Souza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade de Saúde Pública da Universidade de São Paulo 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676767/
https://www.ncbi.nlm.nih.gov/pubmed/29020123
http://dx.doi.org/10.11606/S1518-8787.2017051006952
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author Rodrigues, Poliany Cristiny de Oliveira
Pinheiro, Samya de Lara
Junger, Washington
Ignotti, Eliane
Hacon, Sandra de Souza
author_facet Rodrigues, Poliany Cristiny de Oliveira
Pinheiro, Samya de Lara
Junger, Washington
Ignotti, Eliane
Hacon, Sandra de Souza
author_sort Rodrigues, Poliany Cristiny de Oliveira
collection PubMed
description OBJECTIVE: The objective of this study has been to analyze whether fine particulate matter (PM(2.5)), as well as its synergistic effect with maximum temperature, humidity, and seasons, is associated with morbidity and mortality from cardiovascular diseases. METHODS: This is an ecological study of time series. We have used as outcomes the daily death and hospitalization records of adults aged 45 years and over from 2009 to 2011 of the municipalities of Cuiabá and Várzea Grande, State of Mato Grosso, Brazil. We have used Poisson regression using generalized additive models, assuming a significance level of 5%. The model has been controlled for temporal trend, seasonality, average temperature, humidity, and season effects. Daily concentrations of PM(2.5) (particulate material with aerodynamic diameter less than 2.5 micrometers) have been obtained by converting the values of optical aerosol thickness. Maximum temperature, humidity, and seasons have been separately included in the model as dummy variables for the analysis of the synergistic effect of PM(2.5) with morbidity and mortality from cardiovascular disease. We have calculated the percentage increase of relative risk (%RR) of deaths and hospitalizations for the linear increase of 10 μg/m(3) of PM(2.5). RESULTS: Between 2009 and 2011, the increase in PM(2.5) was associated with a %RR 2.28 (95%CI 0.53–4.06) for hospitalizations on the same day of exposure and RR% 3.57 (95%CI 0.82–6.38) for deaths with a lag of three days. On hot days, %RR 4.90 (95%CI -0.61–9.38) was observed for deaths. No modification of the effect of PM(2.5) was observed for maximum temperature in relation to hospitalizations. On days with low humidity, %RR was 5.35 (95%CI -0.20–11.22) for deaths and 2.71 (95%CI -0.39–5.92) for hospitalizations. In the dry season, %RR was 2.35 (95%CI 0.59–4.15) for hospitalizations and 3.43 (95%CI 0.58–6.35) for deaths. CONCLUSIONS: The PM(2.5) is associated with morbidity and mortality from cardiovascular diseases and its effects may be potentiated by heat and low humidity and during the dry season.
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spelling pubmed-56767672017-11-16 Climatic variability and morbidity and mortality associated with particulate matter Rodrigues, Poliany Cristiny de Oliveira Pinheiro, Samya de Lara Junger, Washington Ignotti, Eliane Hacon, Sandra de Souza Rev Saude Publica Original Articles OBJECTIVE: The objective of this study has been to analyze whether fine particulate matter (PM(2.5)), as well as its synergistic effect with maximum temperature, humidity, and seasons, is associated with morbidity and mortality from cardiovascular diseases. METHODS: This is an ecological study of time series. We have used as outcomes the daily death and hospitalization records of adults aged 45 years and over from 2009 to 2011 of the municipalities of Cuiabá and Várzea Grande, State of Mato Grosso, Brazil. We have used Poisson regression using generalized additive models, assuming a significance level of 5%. The model has been controlled for temporal trend, seasonality, average temperature, humidity, and season effects. Daily concentrations of PM(2.5) (particulate material with aerodynamic diameter less than 2.5 micrometers) have been obtained by converting the values of optical aerosol thickness. Maximum temperature, humidity, and seasons have been separately included in the model as dummy variables for the analysis of the synergistic effect of PM(2.5) with morbidity and mortality from cardiovascular disease. We have calculated the percentage increase of relative risk (%RR) of deaths and hospitalizations for the linear increase of 10 μg/m(3) of PM(2.5). RESULTS: Between 2009 and 2011, the increase in PM(2.5) was associated with a %RR 2.28 (95%CI 0.53–4.06) for hospitalizations on the same day of exposure and RR% 3.57 (95%CI 0.82–6.38) for deaths with a lag of three days. On hot days, %RR 4.90 (95%CI -0.61–9.38) was observed for deaths. No modification of the effect of PM(2.5) was observed for maximum temperature in relation to hospitalizations. On days with low humidity, %RR was 5.35 (95%CI -0.20–11.22) for deaths and 2.71 (95%CI -0.39–5.92) for hospitalizations. In the dry season, %RR was 2.35 (95%CI 0.59–4.15) for hospitalizations and 3.43 (95%CI 0.58–6.35) for deaths. CONCLUSIONS: The PM(2.5) is associated with morbidity and mortality from cardiovascular diseases and its effects may be potentiated by heat and low humidity and during the dry season. Faculdade de Saúde Pública da Universidade de São Paulo 2017-11-07 /pmc/articles/PMC5676767/ /pubmed/29020123 http://dx.doi.org/10.11606/S1518-8787.2017051006952 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Rodrigues, Poliany Cristiny de Oliveira
Pinheiro, Samya de Lara
Junger, Washington
Ignotti, Eliane
Hacon, Sandra de Souza
Climatic variability and morbidity and mortality associated with particulate matter
title Climatic variability and morbidity and mortality associated with particulate matter
title_full Climatic variability and morbidity and mortality associated with particulate matter
title_fullStr Climatic variability and morbidity and mortality associated with particulate matter
title_full_unstemmed Climatic variability and morbidity and mortality associated with particulate matter
title_short Climatic variability and morbidity and mortality associated with particulate matter
title_sort climatic variability and morbidity and mortality associated with particulate matter
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676767/
https://www.ncbi.nlm.nih.gov/pubmed/29020123
http://dx.doi.org/10.11606/S1518-8787.2017051006952
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