Cargando…

Experience with ceftaroline for treatment of methicillin-resistant Staphylococcus aureus pneumonia in a community hospital

Background: Methicillin-resistant Staphylococcus a ureus (MRSA) is an organism causing significant mortality and morbidity with nosocomial infections. Ceftaroline is a new cephalosporin antibiotic that has activity against MRSA. In the USA, this antibiotic has not been approved for use in pneumonia...

Descripción completa

Detalles Bibliográficos
Autores principales: Karki, Apurwa, Thurm, Craig, Cervellione, Kelly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676793/
https://www.ncbi.nlm.nih.gov/pubmed/29147471
http://dx.doi.org/10.1080/20009666.2017.1374107
_version_ 1783277127599128576
author Karki, Apurwa
Thurm, Craig
Cervellione, Kelly
author_facet Karki, Apurwa
Thurm, Craig
Cervellione, Kelly
author_sort Karki, Apurwa
collection PubMed
description Background: Methicillin-resistant Staphylococcus a ureus (MRSA) is an organism causing significant mortality and morbidity with nosocomial infections. Ceftaroline is a new cephalosporin antibiotic that has activity against MRSA. In the USA, this antibiotic has not been approved for use in pneumonia caused by MRSA. Objectives: To review the use of ceftaroline in MRSA pneumonia in a US hospital and evaluate its clinical success. Methods: A retrospective study was conducted in an urban community hospital assessing the use of ceftaroline for MRSA pneumonia. Results: The clinical success was comparable to the currently approved treatment for MRSA pneumonia. Conclusion: The results of our study showed a favorable result for the treatment of MRSA pneumonia. Well-designed studies need to be performed for further validation of these results.
format Online
Article
Text
id pubmed-5676793
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Taylor & Francis
record_format MEDLINE/PubMed
spelling pubmed-56767932017-11-16 Experience with ceftaroline for treatment of methicillin-resistant Staphylococcus aureus pneumonia in a community hospital Karki, Apurwa Thurm, Craig Cervellione, Kelly J Community Hosp Intern Med Perspect Research Articles Background: Methicillin-resistant Staphylococcus a ureus (MRSA) is an organism causing significant mortality and morbidity with nosocomial infections. Ceftaroline is a new cephalosporin antibiotic that has activity against MRSA. In the USA, this antibiotic has not been approved for use in pneumonia caused by MRSA. Objectives: To review the use of ceftaroline in MRSA pneumonia in a US hospital and evaluate its clinical success. Methods: A retrospective study was conducted in an urban community hospital assessing the use of ceftaroline for MRSA pneumonia. Results: The clinical success was comparable to the currently approved treatment for MRSA pneumonia. Conclusion: The results of our study showed a favorable result for the treatment of MRSA pneumonia. Well-designed studies need to be performed for further validation of these results. Taylor & Francis 2017-10-18 /pmc/articles/PMC5676793/ /pubmed/29147471 http://dx.doi.org/10.1080/20009666.2017.1374107 Text en © 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Karki, Apurwa
Thurm, Craig
Cervellione, Kelly
Experience with ceftaroline for treatment of methicillin-resistant Staphylococcus aureus pneumonia in a community hospital
title Experience with ceftaroline for treatment of methicillin-resistant Staphylococcus aureus pneumonia in a community hospital
title_full Experience with ceftaroline for treatment of methicillin-resistant Staphylococcus aureus pneumonia in a community hospital
title_fullStr Experience with ceftaroline for treatment of methicillin-resistant Staphylococcus aureus pneumonia in a community hospital
title_full_unstemmed Experience with ceftaroline for treatment of methicillin-resistant Staphylococcus aureus pneumonia in a community hospital
title_short Experience with ceftaroline for treatment of methicillin-resistant Staphylococcus aureus pneumonia in a community hospital
title_sort experience with ceftaroline for treatment of methicillin-resistant staphylococcus aureus pneumonia in a community hospital
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676793/
https://www.ncbi.nlm.nih.gov/pubmed/29147471
http://dx.doi.org/10.1080/20009666.2017.1374107
work_keys_str_mv AT karkiapurwa experiencewithceftarolinefortreatmentofmethicillinresistantstaphylococcusaureuspneumoniainacommunityhospital
AT thurmcraig experiencewithceftarolinefortreatmentofmethicillinresistantstaphylococcusaureuspneumoniainacommunityhospital
AT cervellionekelly experiencewithceftarolinefortreatmentofmethicillinresistantstaphylococcusaureuspneumoniainacommunityhospital