An efficient synthesis of indolo[2,3-b]quinoline guanidine derivatives with their in vitro and in vivo study

An optimization of the guanidylation process by verifying the efficacy of common guanylation reagents in order to obtain the guanidine derivatives of indolo[2,3-b]quinoline has been performed. As a result, a high-yield procedure using N,N′-di-Boc-N′′-triflylguanidine was applied to synthesize the gu...

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Detalles Bibliográficos
Autores principales: Sidoryk, Katarzyna, Świtalska, Marta, Rózga, Piotr, Wietrzyk, Joanna, Bujak, Iwona, Żerek, Bartłomiej, Kaczmarek, Łukasz, Cybulski, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676820/
https://www.ncbi.nlm.nih.gov/pubmed/29170613
http://dx.doi.org/10.1007/s00044-017-2028-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676820/
https://www.ncbi.nlm.nih.gov/pubmed/29170613
http://dx.doi.org/10.1007/s00044-017-2028-1

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