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An efficient synthesis of indolo[2,3-b]quinoline guanidine derivatives with their in vitro and in vivo study
An optimization of the guanidylation process by verifying the efficacy of common guanylation reagents in order to obtain the guanidine derivatives of indolo[2,3-b]quinoline has been performed. As a result, a high-yield procedure using N,N′-di-Boc-N′′-triflylguanidine was applied to synthesize the gu...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676820/ https://www.ncbi.nlm.nih.gov/pubmed/29170613 http://dx.doi.org/10.1007/s00044-017-2028-1 |