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Complex evolutionary footprints revealed in an analysis of reused protein segments of diverse lengths

Proteins share similar segments with one another. Such “reused parts”—which have been successfully incorporated into other proteins—are likely to offer an evolutionary advantage over de novo evolved segments, as most of the latter will not even have the capacity to fold. To systematically explore th...

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Detalles Bibliográficos
Autores principales: Nepomnyachiy, Sergey, Ben-Tal, Nir, Kolodny, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676897/
https://www.ncbi.nlm.nih.gov/pubmed/29078314
http://dx.doi.org/10.1073/pnas.1707642114