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Alzheimer’s Disease as the Product of a Progressive Energy Deficiency Syndrome in the Central Nervous System: The Neuroenergetic Hypothesis
The decreased availability of metabolizable energy resources in the central nervous system is hypothesized to be a key factor in the pathogenesis of Alzheimer’s disease. More specifically, the age-related decline in the ability of glucose to cross the blood-brain barrier creates a metabolic stress t...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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IOS Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676979/ https://www.ncbi.nlm.nih.gov/pubmed/28946565 http://dx.doi.org/10.3233/JAD-170549 |