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Proton irradiation: a key to the challenge of N-glycosidic bond formation in a prebiotic context

The formation of nucleosides in abiotic conditions is a major hurdle in origin-of-life studies. We have determined the pathway of a general reaction leading to the one-pot synthesis of ribo- and 2′-deoxy-ribonucleosides from sugars and purine nucleobases under proton irradiation in the presence of a...

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Detalles Bibliográficos
Autores principales: Saladino, Raffaele, Bizzarri, Bruno M., Botta, Lorenzo, Šponer, Jiří, Šponer, Judit E., Georgelin, Thomas, Jaber, Maguy, Rigaud, Baptiste, Kapralov, Mikhail, Timoshenko, Gennady N., Rozanov, Alexei, Krasavin, Eugene, Timperio, Anna Maria, Mauro, Ernesto Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677017/
https://www.ncbi.nlm.nih.gov/pubmed/29116184
http://dx.doi.org/10.1038/s41598-017-15392-8