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Proton irradiation: a key to the challenge of N-glycosidic bond formation in a prebiotic context
The formation of nucleosides in abiotic conditions is a major hurdle in origin-of-life studies. We have determined the pathway of a general reaction leading to the one-pot synthesis of ribo- and 2′-deoxy-ribonucleosides from sugars and purine nucleobases under proton irradiation in the presence of a...
Autores principales: | Saladino, Raffaele, Bizzarri, Bruno M., Botta, Lorenzo, Šponer, Jiří, Šponer, Judit E., Georgelin, Thomas, Jaber, Maguy, Rigaud, Baptiste, Kapralov, Mikhail, Timoshenko, Gennady N., Rozanov, Alexei, Krasavin, Eugene, Timperio, Anna Maria, Mauro, Ernesto Di |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677017/ https://www.ncbi.nlm.nih.gov/pubmed/29116184 http://dx.doi.org/10.1038/s41598-017-15392-8 |
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