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Injection of high dose botulinum-toxin A leads to impaired skeletal muscle function and damage of the fibrilar and non-fibrilar structures

Botulinum-toxin A (BoNT/A) is used for a wide range of conditions. Intramuscular administration of BoNT/A inhibits the release of acetylcholine at the neuromuscular junction from presynaptic motor neurons causing muscle-paralysis. The aim of the present study was to investigate the effect of high do...

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Detalles Bibliográficos
Autores principales: Pingel, Jessica, Nielsen, Mikkel Schou, Lauridsen, Torsten, Rix, Kristian, Bech, Martin, Alkjaer, Tine, Andersen, Ida Torp, Nielsen, Jens Bo, Feidenhansl, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677119/
https://www.ncbi.nlm.nih.gov/pubmed/29116170
http://dx.doi.org/10.1038/s41598-017-14997-3

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