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Injection of high dose botulinum-toxin A leads to impaired skeletal muscle function and damage of the fibrilar and non-fibrilar structures
Botulinum-toxin A (BoNT/A) is used for a wide range of conditions. Intramuscular administration of BoNT/A inhibits the release of acetylcholine at the neuromuscular junction from presynaptic motor neurons causing muscle-paralysis. The aim of the present study was to investigate the effect of high do...
Autores principales: | Pingel, Jessica, Nielsen, Mikkel Schou, Lauridsen, Torsten, Rix, Kristian, Bech, Martin, Alkjaer, Tine, Andersen, Ida Torp, Nielsen, Jens Bo, Feidenhansl, R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677119/ https://www.ncbi.nlm.nih.gov/pubmed/29116170 http://dx.doi.org/10.1038/s41598-017-14997-3 |
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