The Ubiquitin Ligase (E3) Psh1p Is Required for Proper Segregation of both Centromeric and Two-Micron Plasmids in Saccharomyces cerevisiae

Protein degradation by the ubiquitin-proteasome system is essential to many processes. We sought to assess its involvement in the turnover of mitochondrial proteins in Saccharomyces cerevisiae. We find that deletion of a specific ubiquitin ligase (E3), Psh1p, increases the abundance of a temperature...

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Detalles Bibliográficos
Autores principales: Metzger, Meredith B., Scales, Jessica L., Dunklebarger, Mitchell F., Weissman, Allan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677152/
https://www.ncbi.nlm.nih.gov/pubmed/28928274
http://dx.doi.org/10.1534/g3.117.300227