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Hypothermic machine perfusion with metformin-University of Wisconsin solution for ex vivo preservation of standard and marginal liver grafts in a rat model
AIM: To compare the effect of University of Wisconsin (UW) solution with or without metformin, an AMP-activated protein kinase (AMPK) activator, for preserving standard and marginal liver grafts of young and aged rats ex vivo by hypothermic machine perfusion (HMP). METHODS: Eighteen young (4 mo old)...
Autores principales: | Chai, Yi-Chao, Dang, Guo-Xin, He, Hai-Qi, Shi, Jian-Hua, Zhang, Hong-Ke, Zhang, Rui-Tao, Wang, Bo, Hu, Liang-Shuo, Lv, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677206/ https://www.ncbi.nlm.nih.gov/pubmed/29142469 http://dx.doi.org/10.3748/wjg.v23.i40.7221 |
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