Association between ABO blood group and severity of coronary artery disease in unstable angina

BACKGROUND: ABO blood groups are genetically transmitted through chromosome 9 at locus 9q34. It is supposed that there is a locus on 9p21, which has a role in developing coronary artery disease. METHODS: Our study population consisted of 309 patients with unstable angina admitted to the Ziaeian Hosp...

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Autores principales: Omidi, Negar, Rafie Khorgami, Mohammad, Effatpanah, Mohammad, Khatami, Farnaz, Mashhadizadeh, Mehrpouya, Jalali, Arash, Hekmat, Hamidreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677320/
https://www.ncbi.nlm.nih.gov/pubmed/29147127
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author Omidi, Negar
Rafie Khorgami, Mohammad
Effatpanah, Mohammad
Khatami, Farnaz
Mashhadizadeh, Mehrpouya
Jalali, Arash
Hekmat, Hamidreza
author_facet Omidi, Negar
Rafie Khorgami, Mohammad
Effatpanah, Mohammad
Khatami, Farnaz
Mashhadizadeh, Mehrpouya
Jalali, Arash
Hekmat, Hamidreza
author_sort Omidi, Negar
collection PubMed
description BACKGROUND: ABO blood groups are genetically transmitted through chromosome 9 at locus 9q34. It is supposed that there is a locus on 9p21, which has a role in developing coronary artery disease. METHODS: Our study population consisted of 309 patients with unstable angina admitted to the Ziaeian Hospital, Tehran, Iran, who underwent coronary angiography. The association between types of blood group (O and non-O) with the severity of coronary artery disease was investigated. RESULTS: Compared to the non-O groups, the O group had more severe coronary artery involvement (P = 0.004). CONCLUSION: Our study supports recent suggestions on the association between blood group and coronary artery disease. Further studies are needed to evaluate the effect of blood group on atherosclerosis.
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spelling pubmed-56773202017-11-16 Association between ABO blood group and severity of coronary artery disease in unstable angina Omidi, Negar Rafie Khorgami, Mohammad Effatpanah, Mohammad Khatami, Farnaz Mashhadizadeh, Mehrpouya Jalali, Arash Hekmat, Hamidreza ARYA Atheroscler Original Article BACKGROUND: ABO blood groups are genetically transmitted through chromosome 9 at locus 9q34. It is supposed that there is a locus on 9p21, which has a role in developing coronary artery disease. METHODS: Our study population consisted of 309 patients with unstable angina admitted to the Ziaeian Hospital, Tehran, Iran, who underwent coronary angiography. The association between types of blood group (O and non-O) with the severity of coronary artery disease was investigated. RESULTS: Compared to the non-O groups, the O group had more severe coronary artery involvement (P = 0.004). CONCLUSION: Our study supports recent suggestions on the association between blood group and coronary artery disease. Further studies are needed to evaluate the effect of blood group on atherosclerosis. Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences 2017-07 /pmc/articles/PMC5677320/ /pubmed/29147127 Text en © 2017 Isfahan Cardiovascular Research Center & Isfahan University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Original Article
Omidi, Negar
Rafie Khorgami, Mohammad
Effatpanah, Mohammad
Khatami, Farnaz
Mashhadizadeh, Mehrpouya
Jalali, Arash
Hekmat, Hamidreza
Association between ABO blood group and severity of coronary artery disease in unstable angina
title Association between ABO blood group and severity of coronary artery disease in unstable angina
title_full Association between ABO blood group and severity of coronary artery disease in unstable angina
title_fullStr Association between ABO blood group and severity of coronary artery disease in unstable angina
title_full_unstemmed Association between ABO blood group and severity of coronary artery disease in unstable angina
title_short Association between ABO blood group and severity of coronary artery disease in unstable angina
title_sort association between abo blood group and severity of coronary artery disease in unstable angina
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677320/
https://www.ncbi.nlm.nih.gov/pubmed/29147127
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