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Treatment Planning for Self-Shielded Radiosurgery

A five degree of freedom, robotic, radiosurgical system dedicated to the brain is currently under development. In the proposed design, the machine is entirely self-shielded. The main advantage of a self-shielded system is the simplification of the system's installation, which can reduce the cos...

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Autores principales: Adler, John R., Schweikard, Achim, Achkire, Younes, Blanck, Oliver, Bodduluri, Mohan, Ma, Lijun, Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677342/
https://www.ncbi.nlm.nih.gov/pubmed/29152420
http://dx.doi.org/10.7759/cureus.1663
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author Adler, John R.
Schweikard, Achim
Achkire, Younes
Blanck, Oliver
Bodduluri, Mohan
Ma, Lijun
Zhang, Hui
author_facet Adler, John R.
Schweikard, Achim
Achkire, Younes
Blanck, Oliver
Bodduluri, Mohan
Ma, Lijun
Zhang, Hui
author_sort Adler, John R.
collection PubMed
description A five degree of freedom, robotic, radiosurgical system dedicated to the brain is currently under development. In the proposed design, the machine is entirely self-shielded. The main advantage of a self-shielded system is the simplification of the system's installation, which can reduce the cost of radiosurgery. In this way, more patients can benefit from this minimally invasive and highly effective type of procedure. For technical reasons, space inside the shielded region is limited, which leads to constraints on the design. Here, two axes of rotation move a 3-megavolt linear accelerator around the patient’s head at a source axis distance of 400 millimeters (mm), while the integrated patient table is characterized by two additional rotational, and one translational, degrees of freedom. Eight cone collimators of different diameters are available. The system can change the collimator automatically during treatment, using a collimator wheel. Since the linear accelerator can only move with two rotational axes, it is not possible to reposition the beam translationally (as it is in six degrees of freedom robotic radiosurgery). To achieve translational repositioning, it is necessary to move the patient couch. Thus, translational repositioning must be kept to a minimum during treatment. Our goal in this contribution is a preliminary investigation of dose distributions attainable with this type of design. Thus, we do not intend to design and evaluate the treatment planning system itself, but rather to establish that appropriate dose distributions can be achieved with this design under realistic clinical circumstances. Our simulation suggests that dose gradients and conformity for complex target shapes, corresponding to state-of-the-art systems, can be achieved with this construction, although a detailed evaluation of the system itself would be needed in the future.
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spelling pubmed-56773422017-11-17 Treatment Planning for Self-Shielded Radiosurgery Adler, John R. Schweikard, Achim Achkire, Younes Blanck, Oliver Bodduluri, Mohan Ma, Lijun Zhang, Hui Cureus Neurosurgery A five degree of freedom, robotic, radiosurgical system dedicated to the brain is currently under development. In the proposed design, the machine is entirely self-shielded. The main advantage of a self-shielded system is the simplification of the system's installation, which can reduce the cost of radiosurgery. In this way, more patients can benefit from this minimally invasive and highly effective type of procedure. For technical reasons, space inside the shielded region is limited, which leads to constraints on the design. Here, two axes of rotation move a 3-megavolt linear accelerator around the patient’s head at a source axis distance of 400 millimeters (mm), while the integrated patient table is characterized by two additional rotational, and one translational, degrees of freedom. Eight cone collimators of different diameters are available. The system can change the collimator automatically during treatment, using a collimator wheel. Since the linear accelerator can only move with two rotational axes, it is not possible to reposition the beam translationally (as it is in six degrees of freedom robotic radiosurgery). To achieve translational repositioning, it is necessary to move the patient couch. Thus, translational repositioning must be kept to a minimum during treatment. Our goal in this contribution is a preliminary investigation of dose distributions attainable with this type of design. Thus, we do not intend to design and evaluate the treatment planning system itself, but rather to establish that appropriate dose distributions can be achieved with this design under realistic clinical circumstances. Our simulation suggests that dose gradients and conformity for complex target shapes, corresponding to state-of-the-art systems, can be achieved with this construction, although a detailed evaluation of the system itself would be needed in the future. Cureus 2017-09-08 /pmc/articles/PMC5677342/ /pubmed/29152420 http://dx.doi.org/10.7759/cureus.1663 Text en Copyright © 2017, Adler et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurosurgery
Adler, John R.
Schweikard, Achim
Achkire, Younes
Blanck, Oliver
Bodduluri, Mohan
Ma, Lijun
Zhang, Hui
Treatment Planning for Self-Shielded Radiosurgery
title Treatment Planning for Self-Shielded Radiosurgery
title_full Treatment Planning for Self-Shielded Radiosurgery
title_fullStr Treatment Planning for Self-Shielded Radiosurgery
title_full_unstemmed Treatment Planning for Self-Shielded Radiosurgery
title_short Treatment Planning for Self-Shielded Radiosurgery
title_sort treatment planning for self-shielded radiosurgery
topic Neurosurgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677342/
https://www.ncbi.nlm.nih.gov/pubmed/29152420
http://dx.doi.org/10.7759/cureus.1663
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