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Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123

Kap123, a major karyopherin protein of budding yeast, recognizes the nuclear localization signals (NLSs) of cytoplasmic histones H3 and H4 and translocates them into the nucleus during DNA replication. Mechanistic questions include H3- and H4-NLS redundancy toward Kap123 and the role of the conserve...

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Detalles Bibliográficos
Autores principales:	An, Sojin, Yoon, Jungmin, Kim, Hanseong, Song, Ji-Joon, Cho, Uhn-soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Structural Biology and Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677370/ https://www.ncbi.nlm.nih.gov/pubmed/29035199 http://dx.doi.org/10.7554/eLife.30244

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