Workflow optimization of whole genome amplification and targeted panel sequencing for CTC mutation detection

Genomic characterization of circulating tumor cells (CTCs) may prove useful as a surrogate for conventional tissue biopsies. This is particularly important as studies have shown different mutational profiles between CTCs and ctDNA in some tumor subtypes. However, isolating rare CTCs from whole blood...

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Detalles Bibliográficos
Autores principales: Liu, Haiyan E., Triboulet, Melanie, Zia, Amin, Vuppalapaty, Meghah, Kidess-Sigal, Evelyn, Coller, John, Natu, Vanita S., Shokoohi, Vida, Che, James, Renier, Corinne, Chan, Natalie H., Hanft, Violet R., Jeffrey, Stefanie S., Sollier-Christen, Elodie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677973/
https://www.ncbi.nlm.nih.gov/pubmed/29263843
http://dx.doi.org/10.1038/s41525-017-0034-3

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