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Trans-oceanic genomic divergence of Atlantic cod ecotypes is associated with large inversions

Chromosomal rearrangements such as inversions can play a crucial role in maintaining polymorphism underlying complex traits and contribute to the process of speciation. In Atlantic cod (Gadus morhua), inversions of several megabases have been identified that dominate genomic differentiation between...

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Autores principales: Berg, P R, Star, B, Pampoulie, C, Bradbury, I R, Bentzen, P, Hutchings, J A, Jentoft, S, Jakobsen, K S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677996/
https://www.ncbi.nlm.nih.gov/pubmed/28930288
http://dx.doi.org/10.1038/hdy.2017.54
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author Berg, P R
Star, B
Pampoulie, C
Bradbury, I R
Bentzen, P
Hutchings, J A
Jentoft, S
Jakobsen, K S
author_facet Berg, P R
Star, B
Pampoulie, C
Bradbury, I R
Bentzen, P
Hutchings, J A
Jentoft, S
Jakobsen, K S
author_sort Berg, P R
collection PubMed
description Chromosomal rearrangements such as inversions can play a crucial role in maintaining polymorphism underlying complex traits and contribute to the process of speciation. In Atlantic cod (Gadus morhua), inversions of several megabases have been identified that dominate genomic differentiation between migratory and nonmigratory ecotypes in the Northeast Atlantic. Here, we show that the same genomic regions display elevated divergence and contribute to ecotype divergence in the Northwest Atlantic as well. The occurrence of these inversions on both sides of the Atlantic Ocean reveals a common evolutionary origin, predating the >100 000-year-old trans-Atlantic separation of Atlantic cod. The long-term persistence of these inversions indicates that they are maintained by selection, possibly facilitated by coevolution of genes underlying complex traits. Our data suggest that migratory behaviour is derived from more stationary, ancestral ecotypes. Overall, we identify several large genomic regions—each containing hundreds of genes—likely involved in the maintenance of genomic divergence in Atlantic cod on both sides of the Atlantic Ocean.
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spelling pubmed-56779962017-12-01 Trans-oceanic genomic divergence of Atlantic cod ecotypes is associated with large inversions Berg, P R Star, B Pampoulie, C Bradbury, I R Bentzen, P Hutchings, J A Jentoft, S Jakobsen, K S Heredity (Edinb) Original Article Chromosomal rearrangements such as inversions can play a crucial role in maintaining polymorphism underlying complex traits and contribute to the process of speciation. In Atlantic cod (Gadus morhua), inversions of several megabases have been identified that dominate genomic differentiation between migratory and nonmigratory ecotypes in the Northeast Atlantic. Here, we show that the same genomic regions display elevated divergence and contribute to ecotype divergence in the Northwest Atlantic as well. The occurrence of these inversions on both sides of the Atlantic Ocean reveals a common evolutionary origin, predating the >100 000-year-old trans-Atlantic separation of Atlantic cod. The long-term persistence of these inversions indicates that they are maintained by selection, possibly facilitated by coevolution of genes underlying complex traits. Our data suggest that migratory behaviour is derived from more stationary, ancestral ecotypes. Overall, we identify several large genomic regions—each containing hundreds of genes—likely involved in the maintenance of genomic divergence in Atlantic cod on both sides of the Atlantic Ocean. Nature Publishing Group 2017-12 2017-09-20 /pmc/articles/PMC5677996/ /pubmed/28930288 http://dx.doi.org/10.1038/hdy.2017.54 Text en Copyright © 2017 The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Original Article
Berg, P R
Star, B
Pampoulie, C
Bradbury, I R
Bentzen, P
Hutchings, J A
Jentoft, S
Jakobsen, K S
Trans-oceanic genomic divergence of Atlantic cod ecotypes is associated with large inversions
title Trans-oceanic genomic divergence of Atlantic cod ecotypes is associated with large inversions
title_full Trans-oceanic genomic divergence of Atlantic cod ecotypes is associated with large inversions
title_fullStr Trans-oceanic genomic divergence of Atlantic cod ecotypes is associated with large inversions
title_full_unstemmed Trans-oceanic genomic divergence of Atlantic cod ecotypes is associated with large inversions
title_short Trans-oceanic genomic divergence of Atlantic cod ecotypes is associated with large inversions
title_sort trans-oceanic genomic divergence of atlantic cod ecotypes is associated with large inversions
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677996/
https://www.ncbi.nlm.nih.gov/pubmed/28930288
http://dx.doi.org/10.1038/hdy.2017.54
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