A new lead to NLRP3 inhibition

The discovery of a small molecule inhibitor that targets the inflammasome sensor NLRP3 offers a new path for the development of selective inflammasome blockers with potential therapeutic benefit in a wide range of human diseases (in this issue, see Jiang et al., https://doi.org/10.1084/jem.20171419)...

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Detalles Bibliográficos
Autores principales: Lamkanfi, Mohamed, Dixit, Vishva M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
News
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678032/
https://www.ncbi.nlm.nih.gov/pubmed/29061692
http://dx.doi.org/10.1084/jem.20171848
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author Lamkanfi, Mohamed
Dixit, Vishva M.
author_facet Lamkanfi, Mohamed
Dixit, Vishva M.
author_sort Lamkanfi, Mohamed
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description The discovery of a small molecule inhibitor that targets the inflammasome sensor NLRP3 offers a new path for the development of selective inflammasome blockers with potential therapeutic benefit in a wide range of human diseases (in this issue, see Jiang et al., https://doi.org/10.1084/jem.20171419).
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spelling pubmed-56780322018-05-06 A new lead to NLRP3 inhibition Lamkanfi, Mohamed Dixit, Vishva M. J Exp Med News The discovery of a small molecule inhibitor that targets the inflammasome sensor NLRP3 offers a new path for the development of selective inflammasome blockers with potential therapeutic benefit in a wide range of human diseases (in this issue, see Jiang et al., https://doi.org/10.1084/jem.20171419). The Rockefeller University Press 2017-11-06 /pmc/articles/PMC5678032/ /pubmed/29061692 http://dx.doi.org/10.1084/jem.20171848 Text en © 2017 Lamkanfi and Dixit http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle News
Lamkanfi, Mohamed
Dixit, Vishva M.
A new lead to NLRP3 inhibition
title A new lead to NLRP3 inhibition
title_full A new lead to NLRP3 inhibition
title_fullStr A new lead to NLRP3 inhibition
title_full_unstemmed A new lead to NLRP3 inhibition
title_short A new lead to NLRP3 inhibition
title_sort new lead to nlrp3 inhibition
topic News
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678032/
https://www.ncbi.nlm.nih.gov/pubmed/29061692
http://dx.doi.org/10.1084/jem.20171848
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