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A new lead to NLRP3 inhibition

The discovery of a small molecule inhibitor that targets the inflammasome sensor NLRP3 offers a new path for the development of selective inflammasome blockers with potential therapeutic benefit in a wide range of human diseases (in this issue, see Jiang et al., https://doi.org/10.1084/jem.20171419)...

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Detalles Bibliográficos
Autores principales: Lamkanfi, Mohamed, Dixit, Vishva M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678032/
https://www.ncbi.nlm.nih.gov/pubmed/29061692
http://dx.doi.org/10.1084/jem.20171848

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