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The Kunitz Domain I of Hepatocyte Growth Factor Activator Inhibitor-2 Inhibits Matriptase Activity and Invasive Ability of Human Prostate Cancer Cells

Dysregulation of pericellular proteolysis is often required for tumor invasion and cancer progression. It has been shown that down-regulation of hepatocyte growth factor activator inhibitor-2 (HAI-2) results in activation of matriptase (a membrane-anchored serine protease), human prostate cancer cel...

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Detalles Bibliográficos
Autores principales: Wu, Shang-Ru, Teng, Chen-Hsin, Tu, Ya-Ting, Ko, Chun-Jung, Cheng, Tai-Shan, Lan, Shao-Wei, Lin, Hsin-Ying, Lin, Hsin-Hsien, Tu, Hsin-Fang, Hsiao, Pei-Wen, Huang, Hsiang-Po, Chen, Chung-Hsin, Lee, Ming-Shyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678078/
https://www.ncbi.nlm.nih.gov/pubmed/29118397
http://dx.doi.org/10.1038/s41598-017-15415-4

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