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Valproic Acid Sensitizes Hepatocellular Carcinoma Cells to Proton Therapy by Suppressing NRF2 Activation

Although efficacy of combined histone deacetylase (HDAC) inhibitors and conventional photon radiotherapy is being tested in clinical trials, their combined effect with proton beam radiotherapy has yet to be determined. Here, we compared combined effect of valproic acid (VPA), a class I and II HDAC i...

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Detalles Bibliográficos
Autores principales:	Yu, Jeong Il, Choi, Changhoon, Shin, Sung-Won, Son, Arang, Lee, Ga-Haeng, Kim, Shin-Yeong, Park, Hee Chul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678087/ https://www.ncbi.nlm.nih.gov/pubmed/29118323 http://dx.doi.org/10.1038/s41598-017-15165-3

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