The genomic landscape of malignant peripheral nerve sheath tumors: diverse drivers of Ras pathway activation

Malignant peripheral nerve sheath tumor (MPNST) is an aggressive soft tissue sarcoma. To more fully characterize the genomic landscape of this tumor type, we performed next generation sequencing studies for mutational and copy number analysis. We analyzed whole exome sequencing data from 12 MPNST an...

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Detalles Bibliográficos
Autores principales: Brohl, Andrew S., Kahen, Elliot, Yoder, Sean J., Teer, Jamie K., Reed, Damon R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678116/
https://www.ncbi.nlm.nih.gov/pubmed/29118384
http://dx.doi.org/10.1038/s41598-017-15183-1

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