Cargando…

A metastasis biomarker (MetaSite Breast™ Score) is associated with distant recurrence in hormone receptor-positive, HER2-negative early-stage breast cancer

Metastasis is the primary cause of death in early-stage breast cancer. We evaluated the association between a metastasis biomarker, which we call “Tumor Microenviroment of Metastasis” (TMEM), and risk of recurrence. TMEM are microanatomic structures where invasive tumor cells are in direct contact w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sparano, Joseph A., Gray, Robert, Oktay, Maja H., Entenberg, David, Rohan, Thomas, Xue, Xiaonan, Donovan, Michael, Peterson, Michael, Shuber, Anthony, Hamilton, Douglas A., D’Alfonso, Timothy, Goldstein, Lori J., Gertler, Frank, Davidson, Nancy E., Condeelis, John, Jones, Joan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678158/ https://www.ncbi.nlm.nih.gov/pubmed/29138761 http://dx.doi.org/10.1038/s41523-017-0043-5

Ejemplares similares

Combining TMEM Doorway Score and Mena(Calc) Score Improves the Prediction of Distant Recurrence Risk in HR+/HER2− Breast Cancer Patients
por: Ye, Xianjun, et al.
Publicado: (2022)

Racial disparity in tumor microenvironment and distant recurrence in residual breast cancer after neoadjuvant chemotherapy
por: Kim, Gina, et al.
Publicado: (2023)

Breast Cancer Cell Re-Dissemination from Lung Metastases—A Mechanism for Enhancing Metastatic Burden
por: Borriello, Lucia, et al.
Publicado: (2021)

Validation of an Automated Quantitative Digital Pathology Approach for Scoring TMEM: A Prognostic Biomarker for Metastasis
por: Entenberg, David, et al.
Publicado: (2020)

Autocrine CSF1R signaling mediates switching between invasion and proliferation downstream of TGFβ in claudin-low breast tumor cells
por: Patsialou, Antonia, et al.
Publicado: (2014)

Tumor Microenvironment of Metastasis (TMEM) Doorways Are Restricted to the Blood Vessel Endothelium in Both Primary Breast Cancers and Their Lymph Node Metastases
por: Ginter, Paula S., et al.
Publicado: (2019)

Inflammatory cytokines and distant recurrence in HER2-negative early breast cancer
por: Sparano, Joseph A., et al.
Publicado: (2022)

Cooperative NF-κB and Notch1 signaling promotes macrophage-mediated MenaINV expression in breast cancer
por: Duran, Camille L., et al.
Publicado: (2023)

The Contribution of Race to Breast Tumor Microenvironment Composition and Disease Progression
por: Kim, Gina, et al.
Publicado: (2020)

Chemotherapy-induced metastasis in breast cancer
por: Karagiannis, George S., et al.
Publicado: (2017)

SUN-MKL1 Crosstalk Regulates Nuclear Deformation and Fast Motility of Breast Carcinoma Cells in Fibrillar ECM Microenvironment
por: Sharma, Ved P., et al.
Publicado: (2021)

Hematogenous Dissemination of Breast Cancer Cells From Lymph Nodes Is Mediated by Tumor MicroEnvironment of Metastasis Doorways
por: Coste, Anouchka, et al.
Publicado: (2020)

An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype
por: Shapiro, Irina M., et al.
Publicado: (2011)

Targeting Tie2 in the Tumor Microenvironment: From Angiogenesis to Dissemination
por: Duran, Camille L., et al.
Publicado: (2021)

Quantitative assessment of invasive mena isoforms (Mena(calc)) as an independent prognostic marker in breast cancer
por: Agarwal, Seema, et al.
Publicado: (2012)

HER2 gene status in primary breast cancers and matched distant metastases
por: Tapia, Coya, et al.
Publicado: (2007)

Time-lapsed, large-volume, high-resolution intravital imaging for tissue-wide analysis of single cell dynamics
por: Entenberg, David, et al.
Publicado: (2017)

HER2-low breast cancer: evolution of HER2 expression from primary tumor to distant metastases
por: Cai, Mengyuan, et al.
Publicado: (2023)

Mena(calc), a quantitative method of metastasis assessment, as a prognostic marker for axillary node-negative breast cancer
por: Forse, Catherine L., et al.
Publicado: (2015)

Discordance of HER2-Low between Primary Tumors and Matched Distant Metastases in Breast Cancer
por: Almstedt, Katrin, et al.
Publicado: (2023)

Molecular markers of risk of subsequent invasive breast cancer in women with ductal carcinoma in situ: protocol for a population-based cohort study
por: Rohan, Thomas E, et al.
Publicado: (2021)

Breast cancers with EGFR and HER2 co-amplification favor distant metastasis and poor clinical outcome
por: Guo, Peng, et al.
Publicado: (2017)

Molecular Prognostic Factors for Distant Metastases in Premenopausal Patients with HR+/HER2− Early Breast Cancer
por: Ni, Hua, et al.
Publicado: (2021)

Gene expression profiling in prognosis of distant recurrence in HR-positive and HER2-negative breast cancer patients
por: Huang, Tzu-Ting, et al.
Publicado: (2018)

Association of tumor-infiltrating lymphocytes with distant disease-free survival in the ShortHER randomized adjuvant trial for patients with early HER2+ breast cancer
por: Dieci, M V, et al.
Publicado: (2019)

The EndoPredict score provides prognostic information on late distant metastases in ER+/HER2− breast cancer patients
por: Dubsky, P, et al.
Publicado: (2013)

Lymphovascular invasion, race, and the 21-gene recurrence score in early estrogen receptor-positive breast cancer
por: Makower, Della, et al.
Publicado: (2021)

Towards an immunoscore for triple negative breast cancer (TNBC): lymphocytic infiltrate predicts outcome
por: Adams, Sylvia, et al.
Publicado: (2013)

A new molecular prognostic score for predicting the risk of distant metastasis in patients with HR+/HER2− early breast cancer
por: Gong, Gyungyub, et al.
Publicado: (2017)

Receptor conversion in distant breast cancer metastases
por: Hoefnagel, Laurien DC, et al.
Publicado: (2010)

Radiotherapy in patients with distant metastatic breast cancer
por: Steinauer, Kirsten, et al.
Publicado: (2014)

Macrophages Promote Tumor Cell Extravasation across an Endothelial Barrier through Thin Membranous Connections
por: Genna, Alessandro, et al.
Publicado: (2023)

Surgery Triggers Outgrowth of Latent Distant Disease in Breast Cancer: An Inconvenient Truth?
por: Retsky, Michael, et al.
Publicado: (2010)

The 21-gene recurrence score in early non-ductal breast cancer: a National Cancer Database analysis
por: Makower, Della, et al.
Publicado: (2022)

Visualization of Actin Polymerization in Invasive Structures of Macrophages and Carcinoma Cells Using Photoconvertible β-Actin – Dendra2 Fusion Proteins
por: Dovas, Athanassios, et al.
Publicado: (2011)

Promoter hypermethylation profiling of distant breast cancer metastases
por: Schrijver, Willemijne A. M. E., et al.
Publicado: (2015)

The Role of lncRNAs in the Distant Metastasis of Breast Cancer
por: Wu, Yinan, et al.
Publicado: (2019)

Exploring the relationships between hormone receptor, HER2 status, and bone involvement in the first distant metastases of in Chinese breast cancer patients who lacked HER2 targeted therapy
por: Jia, Zhifeng, et al.
Publicado: (2023)

Impact of hormone receptor status and distant recurrence-free interval on survival benefits from trastuzumab in HER2-positive metastatic breast cancer
por: Yang, Hai-Yuan, et al.
Publicado: (2017)

Targeting HER2-positive breast cancer: advances and future directions
por: Swain, Sandra M., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_kntlbps02ilfgu9985b5gcotsc